Priligy (Dapoxetine): Who Can Take, Contraindications, Side Effects

What is Priligy, and how does it work?

Priligy is a member of the selective serotonin reuptake inhibitor (SSRI) class of medications that are widely used to treat severe occurrences of depression. Unlike other SSRIs, Priligy is too quickly absorbed and evacuated from the body to produce a measurable salutary effect as an antidepressant, but numerous researches have shown it can delay male orgasms by as much as 3 times.

Premature ejaculation has been linked with the deficiency of serotonin neurotransmitters in the brain. These neurotransmitters are messengers between nerve cells that transmit signals, one such signal, in particular, is the nerve message that ultimately triggers ejaculation. Low levels of serotonin activity lead to the deficiency, which, in turn, may lead to quite a few unpleasant physical and psychological symptoms, PE being one of them.

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Quick facts:
- Priligy (dapoxetine) is an oral drug used to delay ejacualtion by up to 30%, when taken on demand.
- The drug is taken 60-120 minutes before sexual activity to ensure maximal results and guarantee ultimate satisfaction for both partners.

Priligy helps by boosting the activity of serotonin neurotransmitters in the brain and, thus, increasing the time it takes a man to ejaculate. In 8 out of 10 patients, the drug helps delay ejaculations by up to three times and gives men more control over their orgasms.

What is male premature ejaculation?

Premature ejaculation is a major problem of men’s sexual health, affecting 20% to 40% of all male population of the planet at some point in time. Premature ejaculation, aka PE, is men’s continued failure to control their ejaculations, which usually occur within one minute of penetration or even prior to it.

What causes PE in men?

There are two different types of male premature ejaculation: primary and acquired. The primary type of PE is usually a lifelong condition that has neurobiological origins. Acquired premature ejaculation happens later in a person’s life and is triggered by psychological or, less frequently, physiological causes. The acquired type of PE is a much better treatable form of this condition.

Premature ejaculation may lead to the loss of self-esteem, decreased sense of self-worth, performance anxiety, depression, and problems in the relationship with sex partners. For most men, PE is a touchy subject that they are not willing to discuss even with their doctor. However, the sooner they admit that the problem exists, the sooner they can deal with it and get back to their regular sexual life.

What are the treatments for premature ejaculation?

Currently, there are several medicinal and non-medicinal treatment options for managing PE symptoms.

Non-medicinal treatments include counselling with a sexual health specialist and using certain behavioural management techniques during sex to delay the onset of ejaculation. They are designed to help people learn more about themselves and their partner’s needs, teach them to handle stress and anxiety, be open about their wishes and expectations, create a safe and encouraging environment that will enable open communication and support.

Medicinal treatments for PE are focused on the use of oral medicinal drugs or topical anaesthetics that delay orgasms. Topical anaesthetics, which are applied to the penis, produce a numbing effect and give the man more time to enjoy sex before he reaches an orgasm. However, there are disadvantages to using such numbing agents, the biggest one being that they only provide short-term on-demand aid and cannot help with the problem in general.

Oral medicines tend to be more beneficial in dealing with PE long-term. Although currently there is no drug approved specifically for the treatment of male PE, doctors often prescribe certain oral medications off-label because of their powerful spin-off effect of delaying orgasms in men. Such oral drugs may include PDE5 inhibitors like Viagra or Cialis, certain antidepressants, and analgesics.

Of all the medications used by men affected by premature ejaculation, the most trusted and effective one is dapoxetine commercially available under the brand name Priligy.

What administration forms and strengths of Priligy are available?

Priligy only comes as oral tablets containing either 30mg or 60mg of dapoxetine. The typical starting dose for new patients begins at 30 milligrams of dapoxetine taken once daily. If this dose proves insufficient, your doctor may decide to gradually increase it to 60 milligrams per day.

Priligy is not designed for continuous daily use; patients should only take the drug when they plan to engage in sex and not more often than once every 24 hours.

How to take Priligy to delay an orgasm?

Priligy is suitable for the on-demand use, meaning a tablet of Priligy should be taken whole with some water 60 to 90 minutes before sex only when the need arises. The drug achieves its maximum concentration in the blood, and therefore, is most effective 1.5-3 hours after its administration.

Combining its administration with heavy meals or alcohol is not advised as it can reduce the effect of the medicine or increase the risk of the development of unwanted side effects.

Do not take more than one tablet of Priligy per day. Doing so will not have a stronger effect on your ejaculations, but may cause OD symptoms or severe adverse reactions.

Who can take Priligy for their PE?

This drug is indicated for the on-demand relief of PE symptoms in adult men of 18-64 years old, who lack the natural ability to control or postpone their ejaculations. Here are the main criteria men need to meet to be diagnosed with premature ejaculation and receive treatment with Priligy:

Men who were not diagnosed with premature ejaculation should not be prescribed a course of treatment with Priligy. The efficiency of Priligy has not been established in men over 65 years old. There is no medical relevancy of Priligy use in patients under the age of 18.

Which side effects can occur after taking Priligy?

The most common side effects resulting from the use of this medication are sickness in the stomach, abdominal pain, diarrhoea, increased perspiration, light-headedness, headache, blurriness of the vision, restlessness, shakes, sleep disturbances, abnormal dreams.

Infrequent and rare side effects of Priligy that might require patients to seek urgent medical assistance include fainting, seizures, rapid mood swings, disorientation, a sudden jump in the heart rate, painful erection followed by the inability to ejaculate.

Men who take Priligy for their PE do not necessarily experience all or any of these symptoms. However, if you feel any uncomfortable or worrying symptoms after taking a pill of Priligy or if your condition worsens with time, call your prescribing physician and get emergency medical help.

Contraindications and restrictions in use of Priligy

The use of Priligy or other dapoxetine-containing meds is contraindicated in patients who suffer from:

This is not an exhaustive list of contraindications for Priligy. Before you start taking this medicine or use it together with other medicines for PE or some different health problems, consult your doctor on its safety and suitability for you.

Where to buy Priligy?

Priligy is a branded Rx medicine that you can buy in many physical and online drugstores if there is a valid prescription present. Cheaper generic versions of this drug are also commercially available and come under many generic brands, including Poxet, Dapox, Prilyxet, and others.

Most of the time, you can purchase generic Priligy online without a doctor’s prescription. However, it is important to remember that only your doctor can knowingly decide if this medicine is safe and useful for you, suggest the most appropriate dose, and inform you on any contraindications, side effects, and precautions it has. Never ignore a licensed doctor’s advice or self-prescribe any medicines.

Note! The information provided on this website and related websites, including information related to diseases and health conditions, treatment methods and products, may be summarized, including information on the packaging and should not be considered in as a substitute for consultation with a doctor. This website does not recommend independent decisions about health and self-medication. The information on this site is not exhaustive about the state of health and does not cover all diseases and methods of their treatment. Consult your doctor as soon as you have questions related to health. Never neglect the advice of a doctor solely on the basis of the information that you have read on our website.